Interleukin-3 (il-3) Promotes Expansion of Hemopoietic-derived Cd45+ Angiogenic Cells and Their Arterial Commitment via Stat5 Activation
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منابع مشابه
Interleukin-3 promotes expansion of hemopoietic-derived CD45+ angiogenic cells and their arterial commitment via STAT5 activation.
Interleukin-3 (IL-3) released by infiltrating inflammatory cells in different pathologic settings contributes to organ and tumor angiogenesis. Here we demonstrate that IL-3 expands a subset of CD45+ circulating angiogenic cells clonally derived from the hemopoietic progenitors. Moreover, CD45+ cells exposed to IL-3 acquire arterial specification and contribute to the formation of vessels in viv...
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تاریخ انتشار 2008